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Gabriel STAN

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Articles signed on MÆDICA, JCM:

Giant Cell Tumor of Long Bones Outcomes of Treatment Corelating with Histopathological Grade

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MÆDICA - a Journal of Clinical Medicine | Vol. 11, nr. 4, 2016
ISSN 1841-9038  |  e-ISSN 2069-6116
ISSN-L 1841-9038
CNCSIS - CMR - B+

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Giant Cell Tumor of Long Bones Outcomes of Treatment Corelating with Histopathological Grade

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ABSTRACT

Introduction: Giant cell tumor (GCT) of bone is a borderline lesion of bones, meaning that in certain conditions it could be transforming in malignant tumor. This article describes the clinical outcome of patients with giant cell tumor of bone and discusses the surgical options for this lesion corelating with histopathological grade.
Material and methods: From 2007 to 2015, 15 patients who met the histological criteria of giant cell tumor of bone were treated at our institution. Diagnosis and histopathological grade were established by biopsy and extemporaneous exam during surgery. Procedure to be selected was decided based on histopathological grade. Outcomes: In all cases the joint functional results were good except 3 cases (20%) where recurrence occurred. In one case the local recurrence was observed after 6 months, and in the other 2 cases, at 3, respectively 5 years after primary treatment. In all 3 cases the initial histopathological exam showed inactive lesions and were treated with curettage and bone grafting.
Conclusion: In our series it was an early reccurence at 6 months and 2 recidives after 2 years.The histopathological exam has significant role in the management of GCT. All inactive lesions were treated by curettage and bone grafting, and active lesions, by curettage and bone cement filling no matter of Campanacci’s grading system. The management is depending mostly on histopathological exam. Low rate of recurrence can be achieved if treatment is selected according to this parameter and with a properly technique.

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Human Gait and Postural Control after Unilateral Total Knee Arthroplasty

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MÆDICA - a Journal of Clinical Medicine | Vol. 9, nr. 4, 2014

ISSN 1841-9038  |  e-ISSN 2069-6116
ISSN-L 1841-9038
CNCSIS - CMR - B+

Human Gait and Postural Control after Unilateral Total Knee Arthroplasty

and

ABSTRACT

Introduction: This study assesses the changes in human gait in the early postoperative phase of unilateral TKA, by evaluating the variability of free moment.

Materials and method: The study group consisted of 10 patients from the Orthopedic Department of the ‘Elias’ University Hospital in Bucharest who undergone unilateral knee arthroplasty with the same type of posterior cruciate ligament substituting prosthesis. For the evaluation of free moment an AMTI AccuGait force platform was used.

Results: Regarding the free moment peaks, for the operated and non-operated limb, increased significantly (p <0.05) in the postoperative period. The stance time was higher post-surgery for both limbs.

Discussion: In the early postoperative phase of unilateral TKA, free moment is higher on both the operated and the non-operated limbs, which means that the knees are subjected to higher torques. Shortly after TKA, patients tend to walk with lower speed, with small steps and reduced cadence. Stance time differences between the operated and the non-operated limbs can lead to overuse of the latter, worsening its condition.

Conclusions: It is highly important to adopt a well-managed rehabilitation program in order to increase walking stability. The cost effectiveness of this procedure could be highly dependent on the rehab program. The parameters studied in this article are useful in assessing the rehabilitation protocol.

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