Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]
A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.
Changes in Fasting Plasma Glucose, HbA1c and Triglycerides Are Related to Changes in Body Composition in Patients with Type 2 Diabetes
Objectives: The objective of this analysis was to evaluate the relationship between the changes in the body composition and the changes in the glycemic control as evaluated by glycemia and glycated hemoglobin (HbA1c) and the lipid metabolism parameters in adults with type 2 diabetes.
Material and Methods: This was a retrospective cohort study, in which we collected data from the files of 171 patients with type 2 diabetes. The patients were followed for 6 months. Body composition (visceral fat area [VFA; cm], body fat mass [BFM, kg] and percent body fat [PBF; %] was assessed by bioelectric impedance. Delta parameters were calculated as the value of the parameter at month 0 minus the value of the parameter at month 3 or month 6.
Outcomes: All body composition parameters decreased significantly from baseline to month 3 and then to month 6. VFA decreased from 176. 26 cm2 at baseline to 151.21 cm² at month 3 and to 146.64 cm² at month 6. PBF decreased from 36.48% to 32.78% at month 3 and to 31.64% at month 6. BFM had a median value of 34.60 kg at baseline and decreased to 29.00 kg at month 3 and 27.95 kg at month 6. At 3 months, delta VAT and delta BFM were correlated with changes in glycemic control and lipid parameters. At 3 months only BFM remained correlated with these parameters.
Conclusion: In the population included in this analysis we showed that changes in VFA and BFM were correlated with changes in glycemic control during the 3-month follow-up period and that changes in BFM were correlated with changes in lipid parameters during the entire follow-up.
Keywords: type 2 diabetes, body composition, glycemic control, triglycerides