SELECT ISSUE


MÆDICA - a Journal of Clinical Medicine | Vol. 14, nr. 1, 2019
ISSN 1841-9038  |  e-ISSN 2069-6116
ISSN-L 1841-9038
CNCSIS - CMR - B+

HIGHLIGHTS

Plagiatul – in actualitate

Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

Members Area


Characteristics of Mannose-Binding Lectin Deficiency in Pediatric Septic Patients – Case Presentation

, , , , , and

ABSTRACT

Mannose binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. The importance of MBL in defence against infections and especially sepsis is still debated. This article discusses recent developments in MBL research and explores how MBL may be operating in the setting of sepsis.
We present the case of a nine-year-old child diagnosed with septic shock but no apparent risk factors, who was found to have low serum levels of mannose-binding lectin on immunological assay.
This case suggests that young children with a genetically determined low MBL production are at a higher risk of developing septic shock.
Keywords: mannose binding-lectin, sepsis, septic shock

Full text | PDF