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MÆDICA - a Journal of Clinical Medicine | Vol. 14, No. 4, 2019
ISSN 1841-9038  |  e-ISSN 2069-6116
ISSN-L 1841-9038
CNCSIS - CMR - B+

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The Effect of pT-TMS on Beta Rhythm in Children with Autism Disorder. A MEG Study

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ABSTRACT

We investigated the beta rhythm in 10 children with autism disorders (six boys and four girls) aged 5-12 (mean± SD: 8.3± 2.1) before and after the application of pico Tesla transcranial magnetic stimulation (pT-TMS) using magnetoencephalography (MEG). The MEG was car-ried out in a magnetically shielded room with a whole-head 122-channel gradiometer. After applying pT-TMS, we observed a beta rhythm increase towards the frequency range of 18-26 Hz in seven out of 10 patients (70%). We created a score that rated the level of improvement for each patient: 1=some change; 2=minor change; and 3=major change. All patients had an improvement in their clinical symptoms after the application of pT-TMS. There was a correlation between the clinical score and the increase of channels in the frequency range 18-26 Hz after pT-TMS. We concluded that the application of pT-TMS affected the beta rhythm in children with autism disorder. Therefore, more studies need to be further conducted.
Keywords: MEG, Fourier transform, autism disorder, beta rhythm

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