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Is there a Role for Spect with 99mTc-Tetrofosmin in the Diagnostic Work Up of a Brain Tumor?
Theodossios BIRBILIS, Nikolaos BOUSSIOS, Lazaros PAPATHEODOSSIOU, Georgios MATIS and Athanassios ZISSIMOPOULOS
ABSTRACT
Brain MRI is the gold standard for diagnosis of brain tumors. In some cases preoperative MRI cannot predict the grade of malignancy, diagnostic information that could be very helpful to the surgeon. In such cases functional imaging with nuclear medicine techniques may prove quite useful.
We present a case of a 58-year-old man with a brain tumor in the parieto-occipital region. Anatomic brain imaging by magnetic resonance imaging was indicative of a low grade astrocytoma. This was followed by planar imaging and single-photon emission computed tomography (SPECT) with 99mTctetrofosmin which showed increased radiotracer accumulation in the lesion, suggesting a glioblastoma which was histologically confirmed. We think that in the MRI era sometimes a 99mTc-tetrofosmin brain scan can contribute to diagnostic workup and improve the final management of the patient.
Keywords: brain tumor, SPECT, diagnosis, 99mTc-tetrofosmin