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Plagiarism’s meaning comes from the Latin word ‘plagiarius,’ which means to kidnap. When someone uses the work of another writer or artist without properly citing the source or giving credit, that’s plagiarism. [...]
Committe on Publication Ethics
A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.
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Teriflunomide – A New Oral Agent for Multiple Sclerosis Treatment
Teriflunomide is an oral immunomodu lator, an active metabolite of leflunomide. Leflunomide is used in the long-term treatment of rheumatoid arthritis and is metabolized to te riflunomide in vivo.
The mechanism of action of teriflunomide is linked to reversibly inhibition of dihydroorotate dehydrogenase, a mithocondrial enzyme involved in de novo synthesis of pyrimidine for DNA replication. The consequence of this mechanism of action is the blockade of activation and proliferation of stimulated lymphocytes (T and B cells).