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Georgiana NICOLAE

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Articles signed on MÆDICA, JCM:

Prenatal Diagnosis in Great Artery Trasposition and Implications in Postnatal Outcome

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MÆDICA - a Journal of Clinical Medicine | Vol. 11, nr. 4, 2016 CNCSIS - CMR - B+ OBBCSSR

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Prenatal Diagnosis in Great Artery Trasposition and Implications in Postnatal Outcome

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ABSTRACT

Great artery transposition, one of the most frequent and severe cyanotic heart malformations, represented the subject of many studies and research up to this moment. Although postnatal period is critical in this pathology, with correct management patients can benefit from complete surgical correction - arterial switch operation with good long term evolution. Prenatal diagnosis of Great Artery Transposition has an important contribution in choosing the appropriate treatment at the right time in postnatal period so that specific complications resulting from delaying the initiation of specific therapies can be avoided. This article proposes a review of existing data at this moment related to the importance of prenatal diagnosis in Great Artery Transposition and underlines how an accurate fetal diagnosis influences the decision of establishing the appropriate treatment in postnatal life for the children with this type of malformation and the complications that can be avoided.
Keywords: Prenatal diagnosis in great artery transposition

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Pulmonary Hypertension in Children – a Practical Approach

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MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 3, 2015 CNCSIS - CMR - B+ OBBCSSR

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Pulmonary Hypertension in Children – a Practical Approach

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ABSTRACT

Pulmonary hypertension (PH) is mean pulmonary arterial pressure above 25 mmHg at rest. Although considered a rare disease, the prevalence of PH in certain risk groups is higher, from 0.5% in patients with HIV infection to 30% in congenital heart disease (CHD) associating PH. In pulmonary arterial hypertension (PAH) associated with CHD, early changes of the vascular bed are reversible after correction of the defect, but there is a point from where the disease becomes irreversible or progression continues despite correction. Among patients with “operable” and “inoperable” CHD, there is a “gray area” group in between, which is defined by pulmonary vascular resistance equal to 4-8 WU/m and ratio of pulmonary vascular resistance to systemic vascular resistance of 0.3-0.5, measured by cardiac catheterization. In this situation a pulmonary vasoreactivity test is indicated. Pulmonary hypertension is a severe disease with increased morbidity and mortality. Pulmonary hypertension can result in death by decreased cardiac output, and heart failure.

Keywords: pulmonary hypertension, congenital heart disease, pulmonary vasoreactivity, nitric oxide administration

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Giant Cardiac Mass Detected to an Infant with Normal Fetal Echography and No Systolic Murmur in Early Postnatal Evolution

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MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 2, 2015

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What is plagiarism

Plagiarism’s meaning comes from the Latin word ‘plagiarius,’ which means to kidnap. When someone uses the work of another writer or artist without properly citing the source or giving credit, that’s plagiarism. [...]

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Giant Cardiac Mass Detected to an Infant with Normal Fetal Echography and No Systolic Murmur in Early Postnatal Evolution

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ABSTRACT

Infective endocarditis is rare in children and is rarer on a normal structural heart in an infant without any surgical intervention. Most cases are related to a pre-existing congenital lesion, the most frequent etiology are Gram-positive cocci and the most feared are fungal agents. This report presents a 7-month-old infant with fungal endocarditis on a normal structural heart. The diagnosis was suspected on clinical examination and was confirmed by echocardiography and positive blood cultures. His particular clinical evolution after medical and surgical treatment illustrates a severe disease with poor prognosis which may be a complication of neonatal intensive care procedures.
Unusual cause of fungal endocarditis in a previously healthy infant: neonatal hospitalization in intensive care unit.

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