MÆDICA - a Journal of Clinical Medicine Logo
  • Home
  • Profile
  • Standards
    • Types of articles
    • Instructions for authors
    • Editing rules (peer-review protocol)
    • Official Journal’s protocols
  • Editorial Council
  • Peer-review TEAM
  • How to
  • Menu

Author archives

  • About
  • Latest Posts

Daniela OPRIS

Latest posts by Daniela OPRIS (see all)

  • Clinical Phenotype of Endothelial Dysfunction in Romanian Scleroderma Patients - March 31, 2016
  • Clinical Phenotype of Endothelial Dysfunction in a Lot of Romanian Scleroderma Patients - December 21, 2015
  • Treatment of Anterior Instability of the Shoulder - June 30, 2015

Articles signed on MÆDICA, JCM:

Clinical Phenotype of Endothelial Dysfunction in Romanian Scleroderma Patients

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 11, nr. 1, 2016 CNCSIS - CMR - B+ OBBCSSR

Members Area


Clinical Phenotype of Endothelial Dysfunction in Romanian Scleroderma Patients

Laura GROSEANU, Florian BERGHEA, Andra BALANESCU, Denisa PREDETEANU, Violeta BOJINCA, Ioana SAULESCU, Cosmin CONSTANTINESCU, Daniela OPRIS, Mihai ABOBULUI, Andreea BORANGIU, Maria-Magdalena NEGRU, Violeta VLAD and Ruxandra IONESCU

ABSTRACT

Objective: to identify the particularities of the clinical phenotype of endothelial dysfunction in a lot of Romanian patients from a reference center and compare it to data reported by international registries.

Material and methods: 51 patients were included in a cross-sectional study. The patients were evaluated for the pattern of disease, main visceral involvement, serum markers of disease.

Results: 41.2% patients had history of digital ulcers, 27.45% had pulmonary arterial hypertension; cardiovascular involvement also included: diastolic dysfunction in 31.1% of the patients, global systolic dysfunction in 9.8%, rhythm and conduction disturbances in 19.6%, peripheral vascular disease in 19.6%. Scleroderma renal crisis was identified in 2 patients.

Conclusions: Vascular complications are a major cause of morbidity and mortality in systemic sclerosis. Earlier therapeutic intervention demands improved screening and diagnosis in all cases.

Full text | PDF

Clinical Phenotype of Endothelial Dysfunction in a Lot of Romanian Scleroderma Patients

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 4, 2015 CNCSIS - CMR - B+ OBBCSSR

Members Area


Clinical Phenotype of Endothelial Dysfunction in a Lot of Romanian Scleroderma Patients

Laura GROSEANU, Florian BERGHEA, Andra BALANESCU, Denisa PREDETEANU, Violeta BOJINCA, Ioana SAULESCU, Cosmin CONSTANTINESCU, Daniela OPRIS, Mihai ABOBULUI, Andreea BORANGIU, Maria-Magdalena NEGRU, Violeta VLAD and Ruxandra IONESCU

ABSTRACT

Objective: to identify the particularities of the clinical phenotype of endothelial dysfunction in a lot of Romanian patients from a reference center and compare it to data reported by international registries.

Material and methods: 51 patients were included in a cross sectional study. The patients were evaluated for the pattern of disease, main visceral involvement, serum markers of disease.

Results: 41.2% patients had history of digital ulcers, 27.45% had pulmonary arterial hypertension; cardiovascular involvement also included: diastolic dysfunction in 31.1% of the patients, global systolic dysfunction in 9.8%, rhythm and conduction disturbances in 19.6%, peripheral vascular disease in 19.6%. Scleroderma renal crisis was identified in 2 patients.

Conclusions: Vascular complications are a major cause of morbidity and mortality in systemic sclerosis. Earlier therapeutic intervention demands improved screening and diagnosis in all cases.

Full text | PDF

Treatment of Anterior Instability of the Shoulder

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 2, 2015

CNCSIS - CMR - B+ OBBCSSR

HIGHLIGHTS

What is plagiarism

Plagiarism’s meaning comes from the Latin word ‘plagiarius,’ which means to kidnap. When someone uses the work of another writer or artist without properly citing the source or giving credit, that’s plagiarism. [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

Members Area


Treatment of Anterior Instability of the Shoulder

Marius VLASE, Razvan ENE, Daniela OPRIS and Catalin CIRSTOIU

ABSTRACT

Objectives: The aim of this study is to compare the long term results of the treatment of anterior instability of the shoulder.

Material and method: The study included a total of 37 patients diagnosed with anterior instability of the shoulder, on the basis of clinical data (anamnesis, physical examination) and imaging (X-rays, MRI examination), operated in the Department of Orthopedics and Traumatology – Emergency University Hospital Bucharest, Romania, between 2009-2012. They were divided in 3 groups, according to the surgical technique used (open Bankart, arthroscopic Bankart and Bristow procedure), and the results were evaluated at 2 years postoperatively using Rowe and Constant scores. Statistical analysis was performed using one-way ANOVA test.

Results: There were no intra- or postoperative complications. No reluxations were recorded. Statistically significant differences (F> Fcrit; p <0.05) of the Constant score were recorded between the three groups on the range of movement variable, especially external rotation, their mean values being higher in the group treated arthroscopically compared to the other two groups.

Conclusions: Arthroscopic shoulder stabilization surgery gives the best long time results in terms of functional recovery of the shoulder, objectified by Constant and Rowe scores. Data from the literature show a higher rate of recurrence after arthroscopic interventions, suggesting that the indications of this technique still requires further clarifications. It’s required a more precise preoperative evaluation, in order to detect any lesions associated with Bankart lesion (bone defects of the anterior rim of glenoid, Hill-Sachs lesion, capsular laxity, rotator cuff tears, long head of biceps injuries). Mastering a surgical techniques is not always enough in order to obtain the best results. The choice of proper surgical technique for each patient, however, can significantly reduce the recurrence rate of shoulder dislocation.

Keywords: anterior instability of the shoulder, Bankart lesion, shoulder arthroscopy

Full text | PDF

Dual X-Ray Absorptiometry Whole Body Composition of Bone Tissue in Rheumatoid Arthritis – a CrossSectional Study

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 1, 2015

CNCSIS - CMR - B+ OBBCSSR

Dual X-Ray Absorptiometry Whole Body Composition of Bone Tissue in Rheumatoid Arthritis – a CrossSectional Study

Claudiu POPESCU, Violeta BOJINCA, Daniela OPRIS and Ruxandra IONESCU

ABSTRACT

Objectives: Previous studies of bone tissue in rheumatoid arthritis (RA) using dual X-ray absorptiometry (DXA) concentrated on regions of interest that were used to diagnose osteoporosis. This study aimed to compare the whole body bone tissue (wbBT) of RA patients with healthy subjects and to identify the RA variables which significantly predict wbBT.

Methods: The study was cross-sectionally designed to include postmenopausal RA patients and agematched healthy female controls. All 107 RA patients and all 104 controls underwent clinical examination, laboratory tests and whole body DXA composition, which recorded total and regional bone indices. Non-parametric standard statistical test and regression models after data normalization were used to assess correlations, associations and differences.

Results: Compared to controls, RA patients had significantly lower whole body and regional bone mass (14.9 kg compared to 15.5 kg; p = 0.031). Disease duration (r = -0.402 ; p < 0.001), C-reactive protein (r = -0.279; p = 0.015) and inflammation (2.5% wbBT compared to 2.9%; p = 0.043), radiographic damage (14.3 kg compared to 16.2 kg; p < 0.001), disease activity scores (r = -0.275 ; p = 0.018 for HAQ) are significantly correlated/associated with lower wbBT. Clinical structural damage is associated with lower wbBT and it can significantly predict them (R2 = 0.014; p = 0.001), while glucocorticoid treatment, even in low doses, was associated with lower wbBT percent (2.6% compared to 2.8%; p = 0.045). Treatment with biologics was associated with a lower rate of whole body osteoporosis (0% compared to 22.2%; p = 0.013).

Conclusions: The main associated factors with the generalized bone loss in female RA patients are disease duration and disease activity. Clinical structural damage is the most powerful predictor of the whole body bone loss. These results suggest a general disturbance of skeletal bone metabolism in RA and could explain a greater risk of fragility fractures of non-central sites (e.g. ribs, tibia, ankles etc.) compared to post-menopause osteoporosis.

Full text | PDF



plic-mail[email protected]

 Terms and conditions

© MÆDICA - a Journal of Clinical Medicine - All rights reserved