Author archives

Mircea TAMPA

Latest posts by Mircea TAMPA (see all)

Articles signed on MÆDICA, JCM:

A Challenging Case of Primary Breast Hodgkin’s Lymphoma

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 1, 2015

CNCSIS - CMR - B+ OBBCSSR

A Challenging Case of Primary Breast Hodgkin’s Lymphoma

, , , , , , , and

ABSTRACT

Primary breast lymphoma (PBL) is a rare entity accounting for less than 1% of all breast malignancies. Diagnostic criteria for primary Hodgkin’s lymphoma of the breast are: the presence of sufficient tissue for diagnosis, close interaction between mammary tissue and lymphomatous infiltrate and no evidence or prior diagnosis of widespread lymphoma. Our case illustrates an unusual presentation of Hodgkin’s lymphoma of the breast: clinically as inflammatory breast cancer and core biopsy as granulomatous mastitis, the final diagnosis requiring surgical biopsy. Current information regarding this entity is scant, mainly build upon its rarity. In this paper we assess the clinical presentation, the step-bystep diagnosis, the treatment and the importance of immunohistochemistry in this uncommon condition.

Full text | PDF

Mucinous Breast Cancer: a Review Study of 5 Year Experience from a Hospital-Based Series of Cases

SELECT ISSUE

MÆDICA - a Journal of Clinical Medicine | Vol. 10, nr. 1, 2015

CNCSIS - CMR - B+ OBBCSSR

Mucinous Breast Cancer: a Review Study of 5 Year Experience from a Hospital-Based Series of Cases

, , , , , , , and

ABSTRACT

Background: Mucinous carcinoma (also known as colloid carcinoma) is a particular type of breast cancer characterized by the presence of extracellular mucin and is linked with a more favorable prognosis than invasive breast carcinoma of no special type. Mucinous carcinoma of the breast is an uncommon form of breast tumor, often presenting as a lobulated, moderately well circumscribed mass on mammography, sonography, and MRI imaging. It accounts for 1 to 7% of all breast cancers. Pure mucinous breast carcinomas are rare and account for about 2% of all primary breast carcinomas. Metastatic disease happens at a lower rate than in other types of invasive carcinoma.

Methods: We present our 5 year experience with this particular pathology in a retrospective review study.

Results: We identified 25 patients with mixed and pure mucinous breast cancer, the tumor size varied greatly from 2 to 19 cm in diameter. A subset of mixed mucinous carcinomas (8 cases) showed neuroendocrine differentiation or other associated premalignant lessions.

Conclusion: Mucinous carcinoma of the breast is a rare entity with a favorable prognosis due to low incidence of lymph node metastases. Pure mucinous breast carcinoma has an even rare.

Full text | PDF